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Clinical representation of Colorectal Colon Cancer - OncoCare Malaysia

Colorectal (Colon) Cancer

Personalised treatments designed to fight cancer while minimising side effects.

What is Colorectal (Colon) Cancer?

Colorectal cancer (CRC) develops in the colon or rectum, often beginning as small growths called polyps that can turn cancerous over time if not removed. Because the colon and rectum are part of the digestive tract, colorectal cancer is sometimes referred to as “colon cancer.”

In Malaysia, colorectal cancer is the most common cancer among men and the second most common among women, according to the Malaysia National Cancer Registry (MNCRR 2017–2021). Unfortunately, a significant proportion of patients are still diagnosed at Stage 3 or 4, when the disease is harder to treat effectively.

Clinical representation of - OncoCare Malaysia
Clinical representation of - OncoCare Malaysia

How Common Is Colorectal Cancer in Malaysia?

According to the Global Cancer Observatory (GLOBOCAN 2022), colorectal (colorectum) cancer is the second most common cancer in Malaysia, with 7,150 new cases, making up about 16.2 % of all new cancer diagnoses. 

Historically, Malaysia’s age-standardised incidence rate (ASR) for CRC was estimated at 18.3 per 100,000 (GLOBOCAN) — among the highest in Southeast Asia.

In terms of mortality, CRC has an age-standardised mortality rate around 11.46 per 100,000 for men and 8.05 per 100,000 for women in Malaysia.

In regional registry data (Northern Malaysia, 2008–2017), the ASR remained relatively stable (17.0–20.0 per 100,000) while the mortality rate declined from ~12.7 to ~3.0 per 100,000 over the decade. Lippincott Journals

These figures underscore that colorectal cancer is a significant health burden in Malaysia, and early detection through screening is critically important.

What Are the Signs and Symptoms of Colorectal Cancer?

In its early stages, colorectal cancer may cause no noticeable symptoms. As the cancer grows, symptoms may include:

These symptoms may be caused by other conditions, but if they persist, medical evaluation is important.

Screening for Colorectal Cancer

Early detection through screening saves lives. In Malaysia, guidelines recommend:

  • Faecal Immunochemical Test (FIT) – A stool test to detect hidden blood. Recommended yearly or biennially for adults aged 50 and above, or earlier if high risk
  • Colonoscopy – The gold standard for detecting and removing polyps before they turn cancerous. Typically advised every 10 years for average-risk individuals, sooner if family history or other risk factors are present
  • Flexible Sigmoidoscopy – May be used as an alternative in some cases

Individuals with a family history of colorectal cancer, inflammatory bowel disease, or genetic syndromes such as Lynch syndrome should begin screening earlier and repeat it more frequently.

Clinical representation of - OncoCare Malaysia

How is Colorectal Cancer Diagnosed?

Diagnosis usually involves:

What Are the Causes and Risk Factors of Colorectal Cancer?

While the exact cause is not always known, several risk factors increase the likelihood of developing colorectal cancer:

  • Age 50 and above
  • Family history of colorectal cancer or polyps
  • Hereditary syndromes (e.g., Lynch syndrome)
  • Diet low in fibre and high in red or processed meats
  • Obesity and lack of physical activity
  • Smoking and heavy alcohol intake
  • Inflammatory bowel disease (ulcerative colitis, Crohn’s disease)

What Are the Types of Colorectal Cancer?

The most common types include:

What Are the Stages of Colorectal Cancer?

Staging describes how advanced the cancer is:

Stage 0 (in situ)

Cancer cells limited to the innermost lining

Cancer confined to the colon/rectum wall or slightly beyond, no lymph nodes

Cancer has spread to nearby lymph nodes

Cancer has spread (metastasised) to distant organs like the liver or lungs

The stage at diagnosis is critical in determining treatment and prognosis.

What Are Colorectal Cancer Treatments?

Treatment depends on the stage, overall health, and fertility wishes of the patient.

Polypectomy

(Removal of polyps) during colonoscopy

Surgery

(Laparoscopic or robotic) to remove the tumour and nearby lymph nodes

Surgery + adjuvant chemotherapy

(To reduce recurrence)

Chemoradiation

Often used for rectal cancers before surgery

Systemic chemotherapy

(E.g., FOLFOX, FOLFIRI)

Metastasis-directed treatment

(Surgery, ablation) in selected patients

Palliative treatments

To control symptoms and maintain quality of life

Meet Our Doctors

In Malaysia, our team includes colorectal oncologists, surgeons, radiation specialists, pathologists, nurses and allied health professionals. They work together to deliver personalised treatment and care for every patient.

Photo Dr Yap Beng Khiong for Colorectal Colon Cancer at OncoCare
Dr Ben Yap Beng Khiong
叶明强医生
Consultant Clinical Oncologist
Dr John Low for at OncoCare
Dr John Low Seng Hooi
刘胜辉医生
Consultant Clinical Oncologist
Dr M
Dr Matin Mellor Abdullah
Consultant Clinical Oncologist
Photo Dr Yugarajah Asokumaran for at OncoCare
Dr Yugarajah Asokumaran
Consultant Medical Oncologist