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Clinical representation of - OncoCare Malaysia

Pancreatic Cancer

Personalised treatments designed to fight cancer while minimising side effects.

What is Pancreatic Cancer?

Pancreatic cancer arises when cells in the pancreas begin to grow uncontrollably, forming malignant tumours. The pancreas sits deep in the abdomen, behind the stomach, and has two important functions: producing digestive enzymes to help break down food, and releasing hormones such as insulin to regulate blood sugar.

Because of its location and the lack of obvious early warning signs, pancreatic cancer is often diagnosed late. This makes it one of the most challenging cancers to treat, with outcomes closely tied to how early the disease is detected.

Clinical representation of Pancreatic Cancer - OncoCare Malaysia
Clinical representation of - OncoCare Malaysia

How Common is Pancreatic Cancer in Malaysia?

According to GLOBOCAN 2020, there were around 1,013 new cases and 1,003 deaths from pancreatic cancer annually in Malaysia. Although it is less common than breast, lung, or colorectal cancer, it is one of the most aggressive cancers, with survival rates remaining low worldwide due to late presentation and limited treatment options.

What are the Signs and Symptoms of Pancreatic Cancer?

Early pancreatic cancer may cause no or only vague symptoms. As the disease progresses, patients may notice:

Because these symptoms can mimic other conditions, medical attention is crucial if they persist.

How is Pancreatic Cancer Diagnosed?

Diagnosis usually involves several steps:

  • Blood tests: Checking liver function, blood sugar, and tumour markers like CA 19-9
  • Imaging scans: CT scans, MRI, PET scans, or endoscopic ultrasound to visualise the pancreas and surrounding organs
  • Biopsy: Obtaining a tissue sample, often guided by endoscopy or imaging, to confirm the cancer type

Early and accurate diagnosis is key to determining whether surgery is possible.

Clinical representation of Pancreatic Cancer - OncoCare Malaysia
Clinical representation of - OncoCare Malaysia

What are the Causes and Risk Factors of Pancreatic Cancer?

While the exact causes remain unclear, certain factors may raise risk:

Protective factors include childbirth, breastfeeding, and use of oral contraceptives, which may lower the risk.

What are the Types of Pancreatic Cancer?

Exocrine tumours (Pancreatic ductal adenocarcinoma)

The most common type, accounting for about 90% of cases

Arise from hormone-producing cells, less common but may grow more slowly

Clinical representation of Pancreatic Cancer - OncoCare Malaysia

What are the Stages of Pancreatic Cancer?

Stage I

Cancer is confined to the pancreas

Cancer spreads to nearby tissues or lymph nodes

Tumour involves major blood vessels or extensive lymph nodes

Cancer spreads (metastasises) to distant organs, most often the liver or lungs

What are the Treatments for Pancreatic Cancer?

Treatment depends on the stage, location of the tumour, and patient’s overall health:

Surgery

The only potential cure. The Whipple procedure (pancreaticoduodenectomy) is performed if cancer is confined to the head of the pancreas. Distal pancreatectomy or total pancreatectomy may be used in other cases.

Palliative Care

Focuses on symptom control (e.g. pain, jaundice, digestion issues) and quality of life, especially in advanced stages.

At OncoCare Malaysia, patients may also be offered access to regional clinical trials, which provide opportunities to benefit from new drugs and combination treatments.

Clinical representation of - OncoCare Malaysia

Survival and Prognosis

Pancreatic cancer is one of the most challenging cancers to treat, with outcomes depending greatly on how early it is detected, the stage of disease, and a patient’s overall health. When surgery is possible, survival rates improve significantly. In advanced cases, treatment often focuses on slowing progression, relieving symptoms, and supporting quality of life.

At OncoCare Malaysia, conversations about prognosis are approached with care and clarity. Our specialists take the time to explain what the diagnosis means, outline realistic treatment options, and guide patients and their families in making informed decisions. Every patient is supported with compassion and respect, ensuring their care plan is as individual as their journey.

While pancreatic cancer remains difficult to treat, research and innovation are bringing new possibilities. Advances in surgery, chemotherapy combinations, and targeted therapies are steadily improving outcomes. With ongoing global and regional clinical trials, patients today have access to more options than ever before.

Meet Our Doctors

At OncoCare Malaysia, our multidisciplinary team includes oncologists specialising in gastrointestinal cancers, hepatobiliary and pancreatic surgeons experienced in advanced resections, radiation oncologists, radiologists, and pathologists. Supported by oncology nurses, dietitians, psycho-oncology counsellors, and rehabilitation specialists, they work together to deliver a personalised care plan for every patient.

Photo Dr Yap Beng Khiong for Colorectal Colon Cancer at OncoCare
Dr Ben Yap Beng Khiong
叶明强医生
Consultant Clinical Oncologist
Dr John Low for at OncoCare
Dr John Low Seng Hooi
刘胜辉医生
Consultant Clinical Oncologist
Dr M
Dr Matin Mellor Abdullah
Consultant Clinical Oncologist
Photo Dr Yugarajah Asokumaran for at OncoCare
Dr Yugarajah Asokumaran
Consultant Medical Oncologist